Hair cell recovery in mitotically blocked cultures of the bullfrog saccule
نویسندگان
چکیده
منابع مشابه
Hair cell heterogeneity in the goldfish saccule.
A set of cytological studies performed in the utricle and saccule of Astronotus ocellatus (Teleostei, Percomorphi, Cichlidae) identified two basic types of hair cells and others with some intermediate characteristics. This paper reports on applying the same techniques to the saccule of Carassius auratus (Teleostei, Otophysi, Cyprinidae) and demonstrates similar types of hair cells to those foun...
متن کاملKinetics of the receptor current in bullfrog saccular hair cells.
The receptor current of hair cells from the bullfrog's sacculus was measured by voltage clamp recording across the isolated sensory epithelium. Several hundred hair cells were stimulated en masse by moving the overlying otolithic membrane with a piezoelectrically activated probe. As measured by optical recording of otolithic membrane motion, the step displacement stimuli reached their final amp...
متن کاملSurvival of bundleless hair cells and subsequent bundle replacement in the bullfrog's saccule.
Our senses of hearing and balance depend upon hair cells, the sensory receptors of the inner ear. Millions of people suffer from hearing and balance deficits caused by damage to hair cells as a result of exposure to noise, aminoglycoside antibiotics, and antitumor drugs. In some species such damage can be reversed through the production of new cells. This proliferative response is limited in ma...
متن کاملThe extent of adaptation in bullfrog saccular hair cells.
Positive deflection of the sensory hair bundle of a vertebrate hair cell opens transduction channels to depolarize the cell. In bullfrog saccular hair cells, there is a subsequent adaptation process, whereby the proportion of transduction channels that are open, and thus the receptor current, declines toward the resting value. This occurs because the sensitivity curve, relating open probability...
متن کاملHair Cell Types and Distributions in the Otolithic and Auditory Organs of the Bullfrog
Based on surface morphology, 6 hair cell types have been identified on the sensory epithelia of the bullfrog otolithic and auditory organs. One of these types apparently is the morphogenetic precursor of vibrational and auditory hair cells. Another type, with a kinocilium several times as long as the longest stereocilia, apparently mediates gravistatic sensitivity. A third type, with a bulbed k...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2000
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.97.22.11722